Kidney Regeneration Tissue Engineering. Recent work indicates the feasibility not only to generate kidney cells from patient specific ipscs but to understand the developmental cues guiding their in vitro production. While development of renal tissue engineering is in a steady state due to the complex composition and highly regulated functionality of the kidney cell therapy using stem cells and primary kidney cells has demonstrated promising therapeutic outcomes in terms of restoration of renal functions in aki and ckd.
Yoo tissue engineering of the kidney principles of tissue engineering 10 1016 b978 0 12 818422 6 00047 2 825 843 2020. 4 implant the bioengineered kidney in a host to regenerate kidney tissue. Tissue engineering would help to address this shortcoming by the regeneration of damaged kidney using natural occurring scaffolds seeded with precursor renal cells.
While development of renal tissue engineering is in a steady state due to the complex composition and highly regulated functionality of the kidney cell therapy using stem cells and primary kidney cells has demonstrated promising therapeutic outcomes in terms of restoration of renal functions in aki and ckd.
Tissue engineering would help to address this shortcoming by the regeneration of damaged kidney using natural occurring scaffolds seeded with precursor renal cells. 3 place 3d renal constructs in a bioreactor to precondition and mature. This study demonstrates the reconstitution of kidney tissues in vivo by transplanting fkcs and suggests that fkcs are a possible new cell source for kidney tissue engineering. In situ tissue regeneration is the utilization of the body s own regenerative capability by mobilizing and recruiting host stem or progenitor cells to the injury sites to regenerate or repair injured tissue 19 20 21.