Kidney Tubules Membrane Transport. Transport in the proximal tubule is largely energy dependent and is driven by oxidative metabolism. And membrane suspensions are presented in table 1.
Tubular sodium then undergoes transcellar transport through the luminal membrane via a variety of porters. Within the kidney nephron system there are many areas where active transport is used to exchange substances between the tubules and the capillaries surrounding the nephron. Kidney tubules are an essential component of an organism s blood clearance mechanism recovering essential metabolites from glomerular filtration by active transport.
Alkaline phosphatase was used as the marker enzyme specific for the luminal membrane of proximal tubules whereas the luminal membrane from distal tubules was characterized by its ability to respond to hydrochlorothiazide in terms of a reduction in na transport.
Alkaline phosphatase was used as the marker enzyme specific for the luminal membrane of proximal tubules whereas the luminal membrane from distal tubules was characterized by its ability to respond to hydrochlorothiazide in terms of a reduction in na transport. Kidney tubules are an essential component of an organism s blood clearance mechanism recovering essential metabolites from glomerular filtration by active transport. As mentioned sodium resorption in the proximal tubule is largely actuated through primary active transport via a basolateral nak atpase which generates a strong electrochemical gradient for sodium resorption across the nephronic barrier. Experimentally it can be supported by acetate lactate and a variety of other organic acids.