Role Of Kidney In Vitamin D Metabolism. It could either be exposure to the sun s ultraviolet b radiation. Vitamin d 3 cholecalciferol the natural form of vitamin d is produced in the skin from 7 dehydrocholesterol.
Abnormalities in vitamin d metabolism play a major role in the pathogenesis of secondary hyperparathyroidism in chronic kidney disease. The kidneys play an important role in protein metabolism. The appearance of a polar metabolite of 25 hydroxychotecalciferol has been studied in the intestinal mucosas of nephrectomized rats and rats which have been made uremic by ureter ligation.
The appearance of a polar metabolite of 25 hydroxychotecalciferol has been studied in the intestinal mucosas of nephrectomized rats and rats which have been made uremic by ureter ligation.
Tanaka and deluca 1973 first demonstrated that rats maintained on a low pi diet synthesized predominantly 1 25 oh 2 d and this effect was not diminished by parathyroidectomy. Vitamin d and 25 oh d 3. Recent studies provided evidence for the kidney to be an important organ for the regulation in the metabolism of both fat vitamin a d and water soluble vitamins e g. Vitamin d comes from two sources in people.